Squamous cell skin cancer
Squamous-cell skin cancer, also known as cutaneous squamous-cell carcinoma (cSCC), is one of the main types of skin cancer along with basal cell cancer, and melanoma.[10] It usually presents as a hard lump with a scaly top but can also form an ulcer.[1] Onset is often over months.[4] Squamous-cell skin cancer is more likely to spread to distant areas than basal cell cancer.[11]
The greatest risk factor is high total exposure to ultraviolet radiation from the Sun.[2] Other risks include prior scars, chronic wounds, actinic keratosis, lighter skin, Bowen’s disease, arsenic exposure, radiation therapy, poor immune system function, previous basal cell carcinoma, and HPV infection.[2][12] Risk from UV radiation is related to total exposure, rather than early exposure.[13] Tanning beds are becoming another common source of ultraviolet radiation.[13] It begins from squamous cells found within the skin.[14] Diagnosis is often based on skin examination and confirmed by tissue biopsy.[2][3]
Decreasing exposure to ultraviolet radiation and the use of sunscreen appear to be effective methods of preventing squamous-cell skin cancer.[5][6] Treatment is typically by surgical removal.[2] This can be by simple excision if the cancer is small otherwise Mohs surgery is generally recommended.[2] Other options may include application of cold and radiation therapy.[7] In the cases in which distant spread has occurred chemotherapy or biologic therapy may be used.[7]
As of 2015, about 2.2 million people have cSCC at any given time.[8] It makes up about 20% of all skin cancer cases.[15] About 12% of males and 7% of females in the United States developed cSCC at some point in time.[2] While prognosis is usually good, if distant spread occurs five-year survival is ~34%.[4][5] In 2015 it resulted in about 51,900 deaths globally.[9] The usual age at diagnosis is around 66.[4] Following the successful treatment of one case of cSCC people are at high risk of developing further cases.[2]
Shillington
Shillington is a borough in Berks County, Pennsylvania, United States with a population of 5,273 at the 2010 census[1] nestled amongst other suburbs outside Reading. It is perhaps best known for being the location of the Homestead to Pennsylvania’s First Governor, Thomas Mifflin.[2]
Shillington began in 1860 as part of Cumru Township, when local landowner and borough namesake Samuel Shilling sold some of his lots for residences. The area had an inn, originally built in 1762, called the Three Mile House because it was 3 miles (5 km) from Reading on the Lancaster Pike. The inn was a popular stop for farmers going to the city’s markets, and later it sat near a horse racing track built by Aaron Einstein in 1868. A post office opened in Shillington in 1884. On August 18, 1908, the Quarter Session Court officially incorporated the borough of Shillington as a separate municipality from Cumru Township with a population of 450.[3]Later that year Shillington elected its first official, Adam Rollman, as chief burgess. Borough council meetings were held in various locations over the years until the present town hall was completed in 1932.[3]